Role of Vitamin B6, signs ,symptoms and its deficiency in human body

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Introduction

Vitamin B6 is generally called pyridoxine. It belongs to vitamin B complex and its a water soluble vitamin that can dissolve in water.

Due to its water solubility it can't store in human body like other vitamins therefore it can obtain by the body from diet. It is important for red blood cell formation, nervous system function, energy production and protein metabolism.

It was discovered in 1930 by scientists during nutrition deficiency disease. It exists in three form

★ Phridoxine

★ Pyridoxamine

★ Pyridoxal

Inside the human body  these three form of vitamin B6 converted into pyridoxal phosphate (PLP) and it works as a coenzyme.

Function of Vitamin B6

1. What is the role of vitamin B6 in red blood formation?

Vitamin B6 play vital role in the ★production of Red blood cell formation

★It acts as a coenzyme for the production of heme which is a main part of hemoglobin that contain iron

★ Without sufficient vitamin B6 body can't produce required  red blood cell as a result disease occur

★ Vitamin B helps in the conversion of glycine and succinyl- CoA into heme

2. How vitamin B6 play a role in energy production?

★ It is important for normal energy level and metabolism 

★ Vitamin B6 helps the body to convert food into usable energy

★ It helps in the metabolism of Carbohydrates, fat and protein

★ Assist amino acid metabolism to produce energy when it require

★  It support citric acid  cycle for energy production 

★ Helping  enzymes that convert glycogen into glucose

3. What is the function of vitamin B6 in nervous system?

★ Vitamin B6 helps in healthy brain sugnalling and nervous function

★ Vitamin B6 is important in nervous system that can produce several neurotransmitter 

★Dopamime

★ Serotonine

★Norepinephrine

★( GABA) Gamma amino butyric acid

4. What is  the role of vitamin B in protein metabolism?

★ Vitamin B6 is the most important vitamin for the metabolism of protein

★ It act as a coenzyme in many reaction such as amino acid

* Decarboxylation

 It is the phase in which amino acid used to produce neurotransmitter and vitamin B6 act as a coenzyme 

* Transamination

It is the transmission phase in which amino group transfer from one amino acid to another and vitamin B6 act as a coenzyme

* Deamination

  It is the removal of amino group for the production of energy and vitamin B6 act as a coenzyme

* vitamins are constantly broken down and rebuilt in our body  for this purpose vitamin B6 is most important

5. How vitamin B6 support immune system

* Vitamin B6 contribute in the proper functioning of immune system

* Adequate vitamin B6 contribute to immune system to protect from foreign particle

* It helps to produce lymphocytes 

* Supporting the formation of antibody

* Regulating immune response and inflammation 

6. How vitamin B6 play role in the development of human brain?

* Vitamin B6 is very crucial for brain development especially during childhood and pregnancy 

* It support the formation of neurotransmitter 

* It control learning , mood and memory

*  Helping the formation of protective cover around neuron that is called myelin

7. How vitamin B6 regulate homocysteine level?

* what is homocysteine?

It is a sulphur containing amino acid that is formed after the breaking down of methonine that is obtained from dietary protein

It is an intermediate substance which can quickly convert into other useful substance or convert back into methonine. High level of homocysteine damage blood vessels and cause cardiovascular disease.

* Vitamin B6 participate in the conversion of homocysteine into cysteine

* Reduce the accumulation of cysteine

*  Reduce risk of cardiovascular disease

* Protect blood vessel from damage

What are the sources of vitamin B6?

 It has basically two sources plant and animal

1.Plant source

Potato

Spinach

Banana

Nuts

Beans

Hole grain

2. Animal source

Fish

Liver

Chicken

Milk

Eggs

How much vitamin B6 is Require  for normal healthy person  on daily basis


*Pregnant women= 1.9 mg

*Breastfeeding women= 2.0 mg

*Infants =0.1 – 0.3 mg

*Children= 0.5 – 1 mg

*Adults= 1.3 – 1.7 mg


What are the Signs and symptoms of vitamin B6 deficiency?

Deficiency of vitamin B6  is rare but in some.  case like

*Choronic alcoholism 

*Kidney disease 

*Poor diet

*Malnutrition 

*Certain medication

*Weakness 

*Depression

*Irritability

*Crack lips

*Skin disorder

*Nerve problem

*Mouth source

*Seizure

It happens due to lack of the production of  nurotransmitter 

*Pheripheral neurophathy

*Anemia

What is the toxicity of vitamin B6?

 When vitamin B6 taken in high amount  for long period of time then it cause several problem such as

* Difficulty in walking

* Numbness in limb

* Nerve  damage

* loss of coordination

Fot more about other vitamins and their role in human, visit  this https://healthduhs.blogspot.com/2026/01/vitamin-and-their-function-in-human.html


Reference


 WHO -World Health Organisation
NIH- National Institute Of Health)

 CDC- Centre for Disease Control and prevention

























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